(reviewはすべてinvited reviewです)

Ikenaka, K., Tsukada, Y., Giles, A.C., Arai, T., Nakadera, Y., Nakano, S., Kawai, K., Mochizuki, H., Katsuno, M., Sobue, G. & Mori, I. "A behavior-based drug screening system using a Caenorhabditis elegans model of motor neuron disease" Sci Rep. 9 10104


Aoki, I., Tateyama, M., Shimomura, T., Ihara K., Kubo, Y., Nakano, S., Mori, I. "SLO potassium channels antagonize premature decision making in C. elegans" Commun Biol. 1 123

Yamaguchi, S., Naoki, H., Ikeda, M., Tsukada, Y., Nakano, S., Mori, I., Ishii, S."Identification of Animal Behavioral Strategies by Inverse Reinforcement Learning" PLoS Comput Biol. 14(5): e1006122.

塚田 祐基, 森 郁恵
線虫の温度走性行動における神経活動による温度空間勾配のエンコーディング 生物物理誌 2018年 Vol.58 No.1 031-033 DOI: 10.2142/biophys.58.031


Sasakura, H., Moribe, H., Nakano, M., Ikemoto, K., Takeuchi, K. & Mori, I.
Lifespan extension by peroxidase/dual oxidase-mediated ROS signaling through pyrroloquinoline quinone in C. elegans. J Cell Sci. doi: 10.1242/jcs.202119 Advance Online

Taniguchi, A., Kimura, Y., Mori, I., Nonaka, S., Higashijima, S. I.
Axially-confined in vivo single-cell labeling by primed conversion using blue and red lasers with conventional confocal microscopes. Dev Growth Differ.Dec;59(9):741-748. doi: 10.1111/dgd.12412. Open Access

book chapter

Aoki I., Nakano S. and Mori I. "Molecular Mechanisms of learning in C. elegans", Learning and Memory: A Comprehensive Reference 2nd Edition, Elsevier, pp415-434 publisher link


Tsukada, Y., Yamao, M., Naoki, H., Shimowada, T., Ohnishi, N., Kuhara, A., Ishii, S. & Mori I.
Reconstruction of spatial thermal gradient encoded in thermosensory neuron AFD in Caenorhabditis elegans. J Neurosci. 36(9): 2571-2581 Open access Asia research news

Kobayashi, K., Nakano, S., Amano, M., Tsuboi, D., Nishioka, T., Ikeda, S., Yokoyama, G., Kaibuchi, K. and Mori, I.
Shingle-Cell memory regulates a neural circuit for sensory behavior. Cell Reports 5;14(1):11-21. doi: 10.1016/j.celrep.2015.11.064. Open access 中日新聞での紹介記事 名古屋大学ハイライト論文


Yoshida, A.*, Nakano, S.*, Suzuki, T., Ihara, K., Higashiyama, T. and Mori, I.(*equally contributed)
A glial K+/Cl− cotransporter modifies temperature-evoked dynamics in Caenorhabditis elegans sensory neurons. Genes, Brain and Behavior. doi: 10.1111/gbb.12260 Open access

Fujiwara, M., Hino, T., Miyamoto, R., Inada, H., Mori, I., Koga, M., Miyahara, K., Ohshima, Y., and Ishihara, T.
The Importance of cGMP Signaling in Sensory Cilia for Body Size Regulation in Caenorhabditis elegans.
Genetics 201(4):1497-510. Open access

Yoshinari, Y., Mori, S., Igarashi, R., Sugi, T., Yokota, H., Ikeda, K., Sumiya, H., Mori, I, Tochio, H., *Harada, Y. and Shirakawa, M.
Optically Detected Magnetic Resonance of Nanodiamonds In Vivo; Implementation of Selective Imaging and Fast Sampling.
J Nanosci Nanotechnol. 15(2), 1014-1021 [PubMed]


Aoki, I. and Mori, I.
Molecular biology of thermosensory transduction in C. elegans. Curr Opin Neurobiol. 34:117-124 publisher site

book chapter

Tsukada, Y., Mori, I. "Optogenetics in Caenorhabditis elegans" Optogenetics -Light-Sensing Proteins and Their Applications Methods in Neuroethological Research, Springer publisher link

Goodman, M.B., Klein, M., Lasse, S., Luo, L., Mori, I., Samuel, A., Sengupta, P., Wang, D. "Thermotaxis navigation behavior." WormBook. 2014 Feb 20:1-10. doi: 10.1895/wormbook.1.168.1. Open Access


Ikenaka, K., Kawai, K., Katsuno, M., Huang, Z., Jiang, Y. M., Iguchi, Y., Kobayashi, K., Kimata, T., Waza, M., Tanaka, F., Mori, I., Sobue, G.
dnc-1/dynactin 1 Knockdown Disrupts Transport of Autophagosomes and Induces Motor Neuron Degeneration. PLoS One. 8(2): e54511.Open access


Sasakura, H., Tsukada, Y., Takagi, S. and Mori, I.
Japanese studies on neural circuits and behavior of Caenorhabditis elegans. Front. Neural Circuits 7:187. doi: 10.3389/fncir.2013.00187 Open access

笹倉 寛之, 森 郁恵
線虫C. elegansにおけるモノアミンによる神経制御 生体の科学 64巻4号(2013.08)P.354-359(ISID:2425101470) 特集 予測と意思決定の神経科学

book chapter

Sasakura, H., Mori, I. "Thermosensory Learning in Caenorhabditis elegans" Invertebrate Learning and Memory, Volume 22:124-139 Academic Press

Tsukada, Y., Mori, I. "Behavioral Analysis in Caenorhabditis elegans" Methods in Neuroethological Research, Springer

塚田 祐基, 森 郁恵 "線虫を用いたオプトジェネティクス研究" オプトジェネティクス-光工学と遺伝学による行動制御技術の最前線- NTS出版


Ohnishi, T., Tanizawa, Y., Watanabe, A., Nakamura, T., Ohba, H., Hirata, H., Kaneda, C., Iwayama, Y., Arimoto, T., Watanabe, K., Mori, I., Yoshikawa, T.
Human myo-inositol monophosphatase 2 rescues the nematode thermotaxis mutant ttx-7 more efficiently than IMPA1: functional and evolutionary considerations of the two mammalian myo-inositol monophosphatase genes. J Neurochem. doi: 10.1111/jnc.12112. [Epub ahead of print] [PubMed]

Igarashi, R., Yoshinari, Y., Yokota, H., Sugi, T., Sugihara, F., Ikeda, K., Sumiya, H., Tsuji, S., Mori, I., Tochio, H., Harada, Y., Shirakawa, M.
Real-time background-free selective imaging of fluorescent nanodiamonds in vivo. Nano Lett. 12(11):5726-32. doi: 10.1021/nl302979d. [PubMed]

Nishio, N., Mohri-Shiomi, A., Nishida, Y., Hiramatsu, N., Kodama-Namba, E., Kimura, D., K., Kuhara, A., Mori, I.
A novel and conserved protein AHO-3 is required for thermotactic plasticity associated with feeding states in Caenorhabditis elegans Genes Cells. 17(5):365-386 open access

Kimata, T., Tanizawa, Y., Can, Y., Ikeda, S., Kuhara, A., Mori, I.
Synaptic Polarity Depends on Phosphatidylinositol Signaling Regulated by Myo-inositol Monophosphatase in Caenorhabditis elegans. Genetics 191(2):509-21. [PubMed]


Sasakura H, Mori I.
Behavioral plasticity, learning, and memory in C. elegans. Curr Opin Neurobiol. 23(1):92-9. [PubMed]

Kimata, T., Sasakura, H., Ohnishi, N., Nishio, N., Mori, I.
Thermotaxis of C. elegans as a model for temperature perception, neural information processing and neural plasticity. Worm 1 (1):31-41 open access

塚田 祐基、 森 郁恵
実験医学 2012年10月号 Vol.30 No.16


Aoki, R., Yagami, T., Sasakura, H., Ogura, K., Kajihara, Y., Ibi, M., Miyamae, T., Nakamura, F., Asakura, T., Kanai, Y., Misu, Y., Iino, Y., Ezcurra, M., Schafer, R., W., Mori, I., Goshima, Y.
A Seven-Transmembrane Receptor That Mediates Avoidance Response to Dihydrocaffeic Acid, a Water-Soluble Repellent in Caenorhabditis elegans. J. Neurosci. 31 (46):16603-16610; [PubMed]

Nishida, Y., Sugi, T., Nonomura, M., Mori, I.
Identification of the AFD neuron as the site of action of the CREB protein in Caenorhabditis elegans thermotaxis. EMBO reports 12 855-862 doi:10.1038/embor.2011.120 open access

Sugi, T., Nishida, Y., Mori, I.
Regulation of behavioral plasticity by systemic temperature signaling in Caenorhabditis elegans. Nat. Neurosci. 14(8):984-992 doi:10.1038/nn.2854 [PubMed]First Author'sレビュー

Kuhara, A., Ohnishi, N., Shimowada, T., Mori, I.
Neural coding in a single sensory neuron controlling opposite seeking behaviours in Caenorhabditis elegans. Nat. Commun. 2:355 doi:10.1038/ncomms1352 open access

Miyara, A., Ohta, A., Okochi, Y., Tsukada, Y., Kuhara, A., Mori, I.
Novel and Conserved Protein Macoilin Is Required for Diverse Neuronal Functions in Caenorhabditis elegans. PLoS Genet 7(5): e1001384 doi:10.1371/journal.pgen.1001384 open access

Ohnishi, N., Kuhara, A., Nakamura, F., Okochi, Y., Mori, I.
Bidirectional regulation of thermotaxis by glutamate transmissions in Caenorhabditis elegans. EMBO J. 30(7):1376-1388 [PubMed] (EMBO J. 30, 1192-1194 (2011)にて紹介されました)


Adachi, T., Kunitomo, H., Tomioka, M., Ohno, H., Okochi, Y., Mori, I., Iino Y.
Reversal of salt preference is directed by the insulin/PI3K and Gq/PKC signaling in Caenorhabditis elegans. Genetics 186:1309-1319. [PubMed]

Liu J., Ward A., Gao J., Dong Y., Nishio N., Inada H., Kang L., Yu Y., Ma D., Xu T., Mori I., Xie Z., Xu XZ.
C. elegans phototransduction requires a G protein-dependent cGMP pathway and a taste receptor homolog. Nat. Neurosci. 13(6):715-22. [PubMed]

Jurado, P., Kodama, E., Tanizawa, Y., Mori, I.
Distinct thermal migration behaviors in response to different thermal gradients in Caenorhabditis elegans. Genes, Brain and Behavior 9:120-127. [PubMed]


Mori, I., Sasakura H.
Aging: shall we take the high road?
Curr. Biol. 19 (9):R363-4. [PubMed]


Kuhara, A.*, Okumura, M.*, Kimata, T., Tanizawa, Y., Takano, R., Kimura, K. D., Inada, H., Matsumoto, K., and Mori I.(*equally contributed)
Temperature sensing by an olfactory neuron in a circuit controlling behavior of C. elegans.
Science 320:803-7. [PubMed]
(Nat. Rev. NeuroSci. 9:500-501 とSci. Signal. 1 (19), ec178.にて紹介されました)


Mori I.
A single sensory neuron directs both attractive and repulsive odor preferences.
Neuron 59:839-840.[PubMed]

久原 篤 & 森 郁恵
細胞工学 特集号 行動を支配する遺伝子, Vol.27 No.11, 1106-1111, 2008
飯野雄一 編

久原 篤, 木全 翼, 森 郁恵
実験医学 増刊号 ライブイメージングで解き明かす多彩な生命現象,東京,羊土社,Vol. 26, No. 17, 89-95, 2008
宮脇敦史 編

久原 篤 & 森 郁恵
"線虫C. elegansの温度走性をもちいた感覚と学習行動の遺伝学的研究"
生物物理, 48 (3), 167-173, 2008

久原 篤, 笹倉 寛之, 木全 翼, 森 郁恵
蛋白質 核酸 酵素 増刊号 神経の分化, 回路形成, 機能発現, Vol. 53, No.4, 580-586, 2008
三品昌美・山森哲雄・狩野方伸・村上富士夫・貝淵弘三 編


Mori, I., Sasakura, H., Kuhara, A.
Worm thermotaxis: a model system for analyzing thermosensation and neural plasticity.
Curr. Opin. Neurobiol. 17:712-719. [PubMed]


久原 篤, 奥村 将年, 森 郁恵
生物の科学 遺伝, No.21, 250-252, 2007

児玉 英志, 久原 篤, 森 郁恵
"線虫C. elegansにおける温度走性行動の分子神経ネットワークメカニズム"
蛋白質 核酸 酵素, Vol.52, No.3, 205-213, 2007


Tanizawa, Y., Kuhara, A., Inada, H., Kodama, E., Mizuno, T. and Mori, I.
Inositol Monophosphatase regulates localization of synaptic components and behavior in the mature nervous system of C. elegans.
Genes Dev. 20: 3296-3310. [PubMed]

Kodama, E., Kuhara, A., Mohri-Shiomi, A., Kimura, K. D., Okumura, M., Tomioka, M., Iino, Y. and Mori, I.
Insulin-like signaling and the neural circuit for integrative behavior in C. elegans.
Genes Dev. 20: 2955-2960. [PubMed]

Kuhara, A. and Mori, I.
Molecular physiology of the neural circuit for calcineurin-dependent associative learning in Caenorhabditis elegans.
J. Neurosci. 26: 9355-9364. [PubMed]

Ito, H.*, Inada, H.* and Mori, I. (*equally contributed)
Quantitative analysis of thermotaxis in the nematode Caenorhabditis elegans.
J. Neurosci. Meth. 154: 45-52. [PubMed]

Inada, H., Ito, H., Satterlee, J., Sengupta, P., Matsumoto, K. and Mori, I.
Identification of guanylyl cyclases that function in thermosensory neurons of Caenorhabditis elegans.
Genetics 172: 2239-2252. [PubMed]


大河内善史、森 郁恵
実験医学 24: 1275-1281.


Okochi, Y., Kimura, K. D., Ohta, A. and Mori, I.
Diverse regulation of sensory signaling by nPKC-epsilon/eta TTX-4 in the nematode C. elegans.
EMBO J. 24: 2127-2137. [PubMed]

Sasakura, H., Inada, H., Kuhara, A., Fusaoka, E., Takemoto, D., Takeuchi, K. and Mori, I.
Maintenance of neuronal positions in organized ganglia by SAX-7, a Caenorhabditis elegans homologue of L1.
EMBO J. 24: 1477-1488. [PubMed]

Mohri, A., Kodama, E., Kimura, K. D., Koike, M., Mizuno, T. and Mori, I.
Genetic Control of Temperature Preference in the Nematode Caenorhabditis elegans.
Genetics 169: 1437-1450. [PubMed]


Kimura, K. D., Miyawaki, A., Matsumoto, K. and Mori, I.
The C. elegans Thermosensory Neuron AFD Responds to Warming.
Curr. Biol. 14: 1291-1295. [PubMed]

Shimozono, S., Fukano, T., Kimura, K. D., Mori, I. Kirino, Y. and Miyawaki, A.
Slow Ca2+ dynamics in pharyngeal muscles in Caenorhabditis elegans during fast pumping.
EMBO Rep. 5: 521-526. [PubMed]


久原 篤、森 郁恵
「生物の嗅覚系3. 線虫」
香りの百科事典 : 480-483. 丸善出版

Mori, I., Okumura, M., and Kuhara, A.
Molecular neurogenetics of sensory behaviors in the nematode C. elegans
Jpn. J. Neuropsychopharmacol, Vol. 24 No. 4, 239-241.

奥村将年、大河内善史、森 郁恵
蛋白質核酸酵素 49: 444-449.



森 郁恵
線虫ラボマニュアル、三谷昌平編、シュプリンガー・フェアラーク東京 : 49-64.

久原 篤、森 郁恵
線虫究極のモデル動物、飯野・石井編、シュプリンガー・フェアラーク東京 : 101-109.

毛利亮子、森 郁恵
脳の科学 25: 209-215.


Ishihara, I., Iino, Y., Mohri, A., Mori, I., Gengyo-Ando, K., Mitani, S. and Katsura, I.
HEN-1, a secretory protein with a LDL receptor motif, regulates sensory integration and learning in Caenorhabditis elegans.
Cell 109: 639-649. [PubMed]

Kuhara, A., Inada, H., Katsura, I. and Mori, I.
Negative regulation and gain control of sensory neurons by the C. elegans calcineurin TAX-6.
Neuron 33: 751-763. [PubMed]


森 郁恵
特集「分子を感じる」、森 憲作監修、細胞工学 21、No12: 1448-1452.

稲田 仁、森 郁恵
研究者は電気線虫の夢を見るか?:線虫C. elegansの神経発生研究
シリーズバイオサイエンスの新世紀「第11巻 脳の発生・分化・可塑性」、御子柴・清水編、日本生化学会編集 : 42-52.


Satterlee, J. S., Sasakura, H., Kuhara, A., Berkeley, M., Mori, I. and Sengupta, P.
Specification of thermosensory neuron fate in C. elegans requires ttx-1, a Homolog of otd/Otx.
Neuron 31: 943-956. [PubMed]

Gomez, M., De Castro, E., Guarin, E., Sasakura, H., Kuhara, A., Mori, I., Bartfai, T., Bargmann, C. I. and Nef, P.
Ca2+ signaling via the neuronal calcium sensor-1 regulates associative learning and memory in C. elegans.
Neuron 30: 241-248. [PubMed]


Mori, I.
Olfaction, in Encyclopedia of Genetics, eds. Brenner et al.,
Academic Press, London, United Kingdom.

木村幸太郎、森 郁恵
生命の不思議全部見せます:線虫C. elegans
特集「モデル生物」、大矢・貝淵監修、細胞工学21、No. 1: 37-43.

森 郁恵
脳の科学 23: 53-57.



木村幸太郎、森 郁恵
線虫C. elegans, GFPとバイオイメージング
実験医学別冊、ポストゲノム時代の実験講座 : 86-97.

木村幸太郎、森 郁恵
線虫 C. elegansを用いて神経系のメカニズムを探る
バイオイメージング Vol.9、No.1.


Komatsu, H., Jin, Y.-H., L'Etoile, N., Mori, I., Bargmann, C. I., Akaike, N. and Ohshima, Y.
Functional reconsitution of alpha and beta subunits of the C. elegans cyclic nucleotide-gated channels.
Brain Research 821: 160-168. [PubMed]


Mori, I.
Genetics of chemotaxis and thermotaxis in the nematode Caenorhabditis elegans.
Ann. Rev. Genet. 33: 399-422. [PubMed]

森 郁恵
biohistory(生命誌)vol.7、No.3: 20-21.

小松秀俊、森 郁恵
C. elegans の温度走性と記憶・学習
生物物理 222: 97-100.


Coburn, C. M., Mori, I., Ohshima, Y. and Bargmann, C. I.
A cyclic nucleotide-gated channel inhibits sensory axon outgrouwh in larval and adult C. elegans: a dinstinct pathway for maintenance of sensory axon structure.
Development 125: 249-258. [PubMed]


Mori, I. and Ohshima, Y.
Molecular neurogenetics of chemotaxis and thermotaxis in the nematode Caenorhabditis elegans.
BioEssays 19: 1055-1064. [PubMed]

Hobert, O., Mori, I., Yamashita, Y., Honda, H., Ohshima, Y., Liu, Y. and Ruvkun, G.
Regulation of interneuron function in the C. elegans thermoregulatory pathway by the ttx-3 homeobox gene.
Neuron 19: 345-357. [PubMed]


Bargmann, C.I. and Mori, I.
Chemotaxis and thermotaxis.
In C. elegans II. (ed. D.L. Riddle et al.) : 717-737.
Cold Spring Harbor Laboratory, Cold Spring Harbor, New York. [C. elegans II]

小松秀俊、森 郁恵、大島靖美
C. elegansの環状ヌクレオチド依存性チャネルと温度感覚、嗅覚および味覚
細胞工学 16: 1166-1174.


Komatsu. H., Mori, I., Rhee, J.-S., Akaike, N. and Ohshima, Y.
Mutations in a cyclic nucleotide-gated channel lead to abnormal thermosensation and chemosensation in C. elegans.
Neuron 17: 707-718. [PubMed]


Mori, I. and Ohshima, Y.
Neural regulation of thermotaxis in Caenorhabditis elegans.
Nature 376: 344-348. [PubMed]


Ogura, K., Wicky, C., Magnenat, L., Tobler, H., Mori, I., Muller, F. and Ohshima, Y.
Caenorhabditis elegans unc-51 gene required for axonal elongation encodes a novel serine/threonine kinase.
Genes Dev. 8: 2389-2400. [PubMed]


森 郁恵、大島靖美
生体の科学 45: 606-607.



森 郁恵、大島靖美
実験医学 11: 1577-1584.

森 郁恵、大島靖美
化学と生物 31: 448-449.


Mori, I.
Genetic and molecular studies on thermotaxis of the nematode Caenorhabditis elegans.
Research projects in reviews, Nissan Science Foundation 14: 257-258.


森 郁恵、大島靖美
遺伝 45: 44-49.

森 郁恵
朝倉書店、ブレインサイエンス IV: 93-102.

森 郁恵、大島靖美
細胞工学 10: 695-702.


Mori, I., Moerman, D. G. and Waterston, R. H.
Interstrain crosses enhance excision of Tc1 transposable elements in Caenorhabditis elegans.
Mol. Gen. Genet. 220: 251-255. [PubMed]


Mori, I., Moerman, D. G. and Waterston, R. H.
Analysis of a mutator activity necessary for germline transposition and excision of Tc1 transposable element in Caenorhabditis elegans.
Genetics 120: 397-407. [PubMed]

Mori, I., Benian, G. M., Moerman, D. G. and Waterston, R. H.
Transposable element Tc1 of Caenorhabditis elegans recognizes specific target sequences for integration.
Proc. Natl. Acad. Sci. USA 85: 861- 864. [PubMed]