Atsushi Kuhara

English/Japanese

Atsushi Kuhara、Date of Birth November 26, 1976、Blood type AB 　　　　　　e-mail： atsushi_kuhara[-at-]cc.nagoya-u.ac.jp　　*Please replace "[-at-]" with "@".(Anti-SPAM)

Research theme： 　　　・Gain control of sensory neurons and neural circuit for learning behavior 　　　・G protein-coupled thermosensory signaling 　　　・Calcium imaging and quantitative analysis of behavior for computer simulation of neural circuit controling behavior

Academic training 　　　1999　　Nagoya University, Japan B. S. Molecular Biology 　　　2002　　Nagoya University, Japan M. S. Biology 　　　2004　　Nagoya University, Japan Ph.D. (Advisor: Ikue Mori) Biology

Employment 　　　2002−2003　Research fellowship of JSPS, Japan society for the promotion of science (for student, DC) 　　　2004　　　　Research fellowship of JSPS (for post-doc, PD) 　　　2004−2005　Research fellowship of JSPS (for post-doc, PD: new hiring) 　　　2005−　　　Assistant Professor, Department of Biology, Nagoya university, Japan

Honors 　　　2004　　Best Paper Award, Genetics Society of Japan 　　　2005　　Best poster prize, 15th International C. elegans Meeting 　　　2007　　23th Inoue Research Award for Young Scientists, Japan 　　　2007　　Best Paper Award, Genetics Society of Japan 　　　2008　　Nagoya university Grobal COE young scientist award 　　　2007　　21th Brain Science Foundation Fellowship grant, Japan 　　　2007　　Mochida Memorial Foundation for Medical and Pharmaceutical Research Fellowship grant, Japan

Publications Kuhara, A., Okumura M., Kimata T., Tanizawa Y., Takano R., Kimura D. K., Inada H., Matsumoto K., and Mori I. "Temperature sensing by an olfactory neuron in a circuit controlling behavior of C. elegans" Science, 320, 803-807, 2008 Mori, I., Sasakura, H., Kuhara, A. "Worm thermotaxis: a model system for analyzing thermosensation and neural plasticity" Current Opinion in Neurobiology, 17: 712-719, 2007 Tanizawa, Y., Kuhara, A., Inada, H., Kodama, E., Mizuno, T., and Mori, I. "Inositol Monophosphatase regulates localization of synaptic components and behavior in the mature nervous system of C. elegans" Genes & Developement, 20: 3296-3310, 2006 Kodama, E., Kuhara, A., Mohri-Shiomi, A., Kimura, K. D., Okumura, M., Tomioka, M., Iino, Y., and Mori, I. "Insulin-like signaling and the neural circuit for integrative behavior in C. elegans" Genes & Developement, 20: 2955-2960, 2006 Kuhara, A. & Mori, I. " Molecular physiology of the neural circuit for calcineurin dependent associative learning in Caenorhabditis elegans " The Journal of Neuroscience, 26(37): 9355-9364, 2006 "This week in the journal" article Sasakura, H., Inada, H., Kuhara, A., Fusaoka, E., Takemoto, D., Takeuchi, K., and Mori, I. "Maintenance of neuronal positions in organized ganglia by SAX-7, a Caenorhabditis elegans homologue of L1" The EMBO Journal, Vol. 24, 1477-1488, 2005 Kuhara, A., Inada, H., Katsura, I., and Mori, I. "Negative Regulation and Gain Control of Sensory Neurons by the C. elegans Calcineurin TAX-6" Neuron, Vol. 33, 751-763, 2002 Satterlee, J., Sasakura, H., Kuhara, A., Berkeley, M., Mori, I., and Sengupta, P. "Specification of Thermosensory Neuron Fate in C. elegans Requires ttx-1, a Homolog of otd/Otx" Neuron, Vol. 31, 943-956, 2001 Gomez, M., Castro, E. D., Guarin, E., Sasakura, H., Kuhara, A., Mori, I., Bargmann, C. I., and Nef, P. 　 "Ca2+-signaling via the neuronal calcium sensor-1 regulates associative learning and memory in C. elegans" Neuron, Vol. 30, 241-248, 2001 Review Kuhara, A., Kimata, T., & Mori, I. "Optical imaging of activity and connectivity of neural circuit", Jikken Igaku,　Vol.26 No.17, 89-95, 2008(Japanease) Kuhara, A. ＆ Mori, I. "G protein dependent thermosensory behavior in C. elegans" Saiboukougaku,　Vol.27 No.11, 1106-1111, 2008 Kuhara, A. ＆ Mori, I. "Molecular neurogenetics of temperature learning and thermosensation in the nematode C. elegans", Biophysics, 48 (3), 167-173, 2008 Kuhara, A., Sasakura, H., Kimata, T., Mori, I. "Neural circuit mechanism underlying thermotaxis behavior in C. elegans", Protein, neculeic acid, and enzyme,　Vol. 53, No.4, 580-586, 2008 Kuhara, A. "G protein-coupled thermosensation by an olfactory neuron in a neural circuit for thermotaxis behaviour of C. elegans" Best Paper Award of Genetics Society of Japan, Genes ＆ Genetic Systems,　GSJ communications, Vol. 82 No. 6, 2007 (Japanease) Kuhara, A., Okumura, M., ＆ Mori, I. "G protein dependent thermosensory mechanism in thermosensory neuron" Bioscience Genetics,　No.21, 250-252, 2007 (Japanease) Kodama, E., Kuhara, A. ＆ Mori, I. "Molecular neural network mechanisms for thermotaxis behavior in C. elegans" Protein, neculeic acid, and enzyme,　Vol.52, No.3, 205-213, 2007 (Japanease) Mori, I., Okumura, M., and Kuhara, A. "Molecular neurogenetics of sensory behaviors in the nematode C. elegans" Jpn. J. Neuropsychopharmacol, Vol. 24 No. 4, 239-241, 2004 Kuhara, A. "Neural circuit for calcineurin dependent associative learning in C. elegans" Genetics in the 21st century (III)-Best Paper Award of Genetics Society of Japan, Genes ＆ Genetic Systems, Vol. 79 No. 5, 4, 2004 (Japanease) 　Books Kuhara, A. "G protein-mediated temperature sensation in olfactory neuron", Brainscience review 2008, in press (Japanease) Kuhara, A. ＆ Mori, I. "Olfactory system 3. C. elegans", Encyclopedia of odor, 480-483, Maruzenn press, 2004 (Japanease) Kuhara, A. ＆ Mori, I. "neural and behavioral response for sensory stimuli", C. elegans: model animal, 101-109, Springer press, 2003 (Japanease)